L-FMAU FOR THE TREATMENT OF HEPATITIS DELTA VIRAL INFECTION
摘要
A method for the treatment for hepatitis delta infection in a host, that includes administering an effective amount of a nucleoside or a nucleoside analog that suppresses the expression of the hepatitis B surface or preS1 antigen in the host 100-fold or more relative to pretreatment values in vivo; or to not more than 1 microgram per milliliter in vivo. In a preferred embodiment, the nucleoside is L-FMAU, or a pharmaceutically acceptable salt or prodrug thereof.
申请公布号
EP1284720(A2)
申请公布日期
2003.02.26
申请号
EP20010922803
申请日期
2001.03.29
申请人
GEORGETOWN UNIVERSITY;CORNELL RESEARCH FOUNDATION, INC.;UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
