发明名称 |
Antibodies to CD23, derivatives thereof, and their therapeutic uses. |
摘要 |
The invention relates to antibodies which bind to the CD23 (FCepsilonRII) type II molecule particularly altered antibodies including antibodies which bind to the CD23 (FCepsilonRII) type II molecule characterized by an affinity constant equal to or greater than 1x10<SUP>9 </SUP>Ka Mol<SUP>-1</SUP>, the preparation of such antibodies, pharmaceutical compositions which contain such antibodies and their use in therapy particularly in the treatment of autoimmune and inflammatory disorders. |
申请公布号 |
ZA200006312(B) |
申请公布日期 |
2003.02.26 |
申请号 |
ZA20000006312 |
申请日期 |
2000.11.03 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
JEAN-YVES MARCEL PAUL BONNEFOY;JONATHAN HENRY ELLIS;JEAN SHEARIN;SCOTT JAMES CROWE;NICHOLAS TIMOTHY RAPSON |
分类号 |
C12N15/02;A61K38/00;A61K39/395;C07K16/28;C12N15/13 |
主分类号 |
C12N15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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