CANCEROUS METASTASIS INHIBITORS CONTAINING URACIL DERIVATIVES

摘要

Drugs having an inhibitory activity on thymidine phosphorylases and inhibiti ng cancerous metastasis, which contain as the active ingredient uracil derivatives represented by general formula (1) or salts thereof, wherein R1 represents chlorine, bromine, iodine, cyano or lower alkyl; and R2 represent s an optionally substituted 4- to 8-membered heterocycle having nitrogen, optionally substituted amidinothio, guanidino, lower alkylamidino, amino, et c.