| 发明名称 |
Gamma-ketoacid dipeptides as inhibitors of caspase-3 |
| 摘要 |
This invention encompasses the novel compounds of Formula I, which are useful in the treatment of caspase-3 mediated diseases.The invention also encompasses certain pharmaceutical compositions comprising compounds of Formula I as well as methods for treatment of caspase-3 mediated diseases.
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| 申请公布号 |
US6525025(B2) |
申请公布日期 |
2003.02.25 |
| 申请号 |
US20010948244 |
申请日期 |
2001.09.07 |
| 申请人 |
MERCK FROSST CANADA & CO. |
发明人 |
HAN YONGXIN;GIROUX ANDRE;GRIMM ERICH L.;ASPIOTIS RENEE;BLACK CAMERON |
| 分类号 |
C12N9/99;A61K38/55;A61P3/10;A61P9/00;A61P9/10;A61P17/14;A61P21/00;A61P25/00;A61P25/16;A61P25/28;A61P31/04;A61P31/18;A61P37/04;A61P43/00;C07C237/22;C07D213/63;C07D215/22;C07D215/233;C07D217/24;C07D239/34;C07D241/44;C07D271/06;C07D307/86;C07D413/12;C07D495/04;C07K5/06;C07K5/062;C07K5/065;C07K5/078;(IPC1-7):A61K38/00;A61K31/195;A01N37/12;A01N37/44;C07C205/00 |
主分类号 |
C12N9/99 |
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