摘要 |
Certain novel 4-substituted N-acylated piperidine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity, diabetes, sexual dysfunction, including erectile dysfunction and female sexual dysfunction. |
申请人 |
MERCK & CO., INC.;GOULET, MARK, T.;NARGUND, RAVI, P.;SEBHAT, IYASSU, K.;UJJAINWALLA, FEROZE;WALSH, THOMAS, F.;WARNER, DANIEL;YE, ZHIXIONG;YOUNG, JONATHAN, R.;BAKSHI, RAMAN, K. |
发明人 |
GOULET, MARK, T.;NARGUND, RAVI, P.;SEBHAT, IYASSU, K.;UJJAINWALLA, FEROZE;WALSH, THOMAS, F.;WARNER, DANIEL;YOUNG, JONATHAN, R.;BAKSHI, RAMAN, K. |