PROCESS FOR PREPARATION OF 5−METHYL−1−PHENYL−2(1H) −PYRIDINONE

摘要

A process for the preparation of 5−methyl−1−phenyl−2(1H) −pyridinone of the general formula (2) useful as an original drug, which can dispense with special reagents and apparatuses and by which the objective compound can be obtained in decreased steps by easy operation. That is, a process for the preparation of 5−methyl−1−phenyl−2(1H)−pyridinone represented by the general formula (2), characterized by reacting 5−methyl −2(1H)−pyridinone represented by the general formula (1) with bromobenzene or chlorobenzene in the presence of both at least one copper catalyst selected from among cuprous catalysts and cupric catalysts and a base.