发明名称 |
MODULATION OF GENE EXPRESSION ASSOCIATED WITH INFLAMMATION PROLIFERATION AND NEURITE OUTGROWTH, USING NUCLEIC ACID BASED TECHNOLOGIES |
摘要 |
The present invention relates to nucleic acid molecules, including antisense, enzymatic nucleic acid molecules, and RNA interference molecules, such as hammerhead ribozymes, DNAzymes, allozymes, siRNA, decoys and antisense, which modulate the expression of prostaglandin D2 (PTGDS), prostaglandin D2 receptor (PTGDR), adenosine receptor, NOGO and NOGO receptor, and IKK genes, such as IKK-gamma, IKK-alpha, or IKK-beta, and PKR genes. |
申请公布号 |
WO02081628(A3) |
申请公布日期 |
2003.02.20 |
申请号 |
WO2002US10512 |
申请日期 |
2002.04.03 |
申请人 |
RIBOZYME PHARMACEUTICALS, INCORPORATED;BLATT, LAWRENCE;CHOWRIRA, BHARAT;HAEBERLI, PETER;MCSWIGGEN, JAMES;FOSNAUGH, KATHY |
发明人 |
BLATT, LAWRENCE;CHOWRIRA, BHARAT;HAEBERLI, PETER;MCSWIGGEN, JAMES;FOSNAUGH, KATHY |
分类号 |
A61K38/00;A61K48/00;C12N5/00;C12N5/02;C12N15/113 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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