发明名称 |
GLYCOSYLASE VERWENDENDE DETEKTION VON BESTIMMTEN NUKLEINSÄURESEQUENZEN |
摘要 |
PCT No. PCT/IE95/00067 Sec. 371 Date Jan. 8, 1998 Sec. 102(e) Date Jan. 8, 1998 PCT Filed Dec. 21, 1995 PCT Pub. No. WO97/03210 PCT Pub. Date Jan. 30, 1997A novel process is presented for the detection of known mutations and polymorphisms in DNA. This process, termed glycosylase mediated polymorphism detection (GMPD) involves amplification of the target DNA using three normal dNTPs and a fourth modified dNTP, whose base is a substrate for a specific DNA-glycosylase once incorporated into the DNA. |
申请公布号 |
DE69527444(T2) |
申请公布日期 |
2003.02.20 |
申请号 |
DE1995627444T |
申请日期 |
1995.12.21 |
申请人 |
FORFAS (TRADING AS BIORESEARCH IRELAND), DUBLIN;UNIVERSITY COLLEGE CORK-NATIONAL UNIVERSITY OF IRELAND, CORK |
发明人 |
MCCARTHY, VALENTINE;VAUGHAN, MARTIN |
分类号 |
C12N15/09;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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