发明名称 USE AND EVALUATION OF A [2+2] PHOTOADDITION IN IMMOBILIZATION OF OLIGONUCLEOTIDES ON A THREE-DIMENSIONAL HYDROGEL MATRIX
摘要 <p>[2 + 2] photo-attachable functional groups were incorporated in polyacrylamide based hydrogels and synthetic oligonucleotide probes. The probes were photochemically attached by covalent bonding to the three dimensional surface of a hydrogel. The resultant hydrogel microarrays were used for detection of specific target oligonucleotides, including mRNA and DNA, as suitable for expression and single nucleotide polymorphism type microarray analyses.</p>
申请公布号 WO2003014392(A2) 申请公布日期 2003.02.20
申请号 IB2002004038 申请日期 2002.08.09
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