PROCESS FOR THE PREPARATION OF HIGHLY PURE CEFUROXIME AXETIL
摘要
A process for the preparation of highly pure cefuroxime axetil is herein described. The process makes use of a treatment, which allows removing an impurity present in the reagent l-acetoxyethyl bromide and responsible for the formation of cefuroxime dimeric derivatives. The removal of said impurity makes it easier to recover crystalline cefuroxime axetil and allows obtaining an exceptional-quality product.
申请公布号
WO03014126(A1)
申请公布日期
2003.02.20
申请号
WO2002EP08583
申请日期
2002.08.01
申请人
ANTIBIOTICOS S.P.A.;FELISI, CLAUDIO;LONGONI, DAVIDE;ALPEGIANI, MARCO;CABRI, WALTER
发明人
FELISI, CLAUDIO;LONGONI, DAVIDE;ALPEGIANI, MARCO;CABRI, WALTER