TRANSDERMAL DELIVERY OF 5-HT3 ANTAGONISTS

摘要

Adhesive dressings have adhesive comprising a cross-linked block copolymer and a plasticiser, the block copolymer having hard and soft segments, there being chemical cross-linking between the soft segments, the plasticiser being present in an amount of at least 10% by weight of the adhesive, wherein the plasticiser is a high molecular weight, oily ester, are able to carry and deliver enhanced quantities of 5-HT3 antagonists, especially ondansetron and granisetron.