| 发明名称 |
INTERPHENYLENE 7-OXABICYCLIC[2.2.1]HEPTANE OXAZOLES AS PROSTAGLANDIN F2a ANTAGONISTS |
| 摘要 |
The present invention provides novel compounds represented by general formula (I). The novel compounds are PGF2a antagonists, useful in pharmaceutical compositions for treating PGF2a-mediated disease responses such as inflammatory reactions relating to rheumatoid arthritis and psoriasis, reproductive disorders, bronchoconstrictive disorders (asthma), excessive bone breakdown (osteoporosis), peptic ulcers, heart disease, platelet aggregation and thrombosis.
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| 申请公布号 |
WO0222621(B1) |
申请公布日期 |
2003.02.20 |
| 申请号 |
WO2001US28175 |
申请日期 |
2001.09.07 |
| 申请人 |
ALLERGAN INC. |
发明人 |
BURK, ROBERT, M.;DONDE, YARIV;GARST, MICHAEL, E. |
| 分类号 |
A61K31/422;A61P1/04;A61P7/02;A61P9/10;A61P11/06;A61P15/00;A61P17/06;A61P19/02;A61P19/10;A61P29/00;A61P43/00;C07D493/08;(IPC1-7):C07D493/08;A61K31/34 |
主分类号 |
A61K31/422 |
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