PHARMACEUTICAL COMPOSITION CONTAINING CASPASE-8 AND/OR CASPASE-9 USEFUL FOR OVERCOMING GLUCOCORTICOID- AND CANCER THERAPY-INDUCED APOPTOSIS RESISTANCE OF TUMOURS

摘要

Described are pharmaceutical compositions containing a caspase-8 and/or caspase-9 protein and/or (a) DNA sequence(s) encoding a caspase-8 and/or caspase-9 protein and a suitable pharmaceutical carrier. Said compositions are useful for restoring apoptosis sensitivity of glucorticoid-induced resistance of carcinoma cells towards cytotoxic therapy.