发明名称 |
MODULATION OF ANGIOGENESIS BY A-BETA PEPTIDES |
摘要 |
The present invention provides methods and compositions for treating disease s and pathological conditions or processes mediated by undesired and/or uncontrolled angiongenesis (characterized as "angiogenic diseases") by increasing the in vivo concentration of the A.beta. peptide, or biologically active fragments or variants of the A.beta. peptide, within a patient suffering from such diseases, conditions, or processes. The present inventio n also concerns diagnostic methods and kits for detection and measurement of anti-angiogenic A.beta. peptide activity in biological fluids and tissues. Such diagnostic methods and kits can be utilized to screen compounds for potential therapeutic activity in the treatment of Alzheimer's disease.</SDO AB>
|
申请公布号 |
CA2467922(A1) |
申请公布日期 |
2003.02.20 |
申请号 |
CA20022467922 |
申请日期 |
2002.08.12 |
申请人 |
ROSKAMP RESEARCH, LLC |
发明人 |
PARIS, DANIEL;MULLAN, MICHAEL |
分类号 |
A61K38/17;G01N33/68;(IPC1-7):C12N15/12;A61P35/00;C12Q1/00;A61K35/12;G01N33/574 |
主分类号 |
A61K38/17 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|