PERCUTANEOUS ABSORPTION PREPARATIONS

摘要

It is intended to provide external preparations for percutaneous application and compositions therefor whereby a hardly soluble chemical such as a chemic al having an ergoline skeleton can be efficiently absorbed via the skin into th e blood under circulation while avoiding side effects on the digestive system observed in case of oral administration or side effects on the central syste m caused by a rapid increase in the concentration in the blood and a high adhesiveness to the skin can be established. This object can be established by compositions characterized by containing a copolymer having N-vinyl-2- pyrrolidone as one of its constituents and percutaneous absorption preparations characterized by having a drug-containing adhesive layer containing such a composition and a support layer.