| 发明名称 |
NITROGEN-BASED CAMPTOTHECIN DERIVATIVES |
| 摘要 |
(20<i>S</i>) esters of camptothecin analogs are provided. The compounds are (20<i>S</i>) esters of an aminoalkanoic acid or an imidoalkanoic acid and camptothecin, which is optionally substituted at the 7, 9, 10, 11, and 12 positions of the camptothecin ring. The compounds are useful for treating cancer. |
| 申请公布号 |
WO02070525(A3) |
申请公布日期 |
2003.02.20 |
| 申请号 |
WO2002US03798 |
申请日期 |
2002.02.06 |
| 申请人 |
CALIFORNIA PACIFIC MEDICAL CENTER |
发明人 |
YANG, LI-XI;PAN, XIANDAO;WANG, HUIJUAN |
| 分类号 |
A61K31/4375;A61K31/496;A61K31/5377;A61P1/00;A61P11/00;A61P13/08;A61P13/12;A61P15/00;A61P17/00;A61P35/00;A61P35/02;C07B61/00;C07D491/22 |
主分类号 |
A61K31/4375 |
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