The invention relates to benzoquinone ansamycin analogs useful for the treatment of cancer and other diseases or conditions characterized by undesired cellular proliferation or hyperproliferation. Therapies involving the administration of such benzoquinone ansamycin analogs, optionally in combination with an inhibitor of an HSP90 client protein, are useful to treat cancer and non-cancerous disease conditions.
申请公布号
WO03013430(A2)
申请公布日期
2003.02.20
申请号
WO2002US24891
申请日期
2002.08.05
申请人
KOSAN BIOSCIENCES, INC.
发明人
SANTI, DANIEL;MYLES, DAVID, C.;TIAN, ZQ;HUTCHINSON, C., RICHARD;JOHNSON, ROBERT;ZHOU, YI-QING;FENG, LI