USE OF XYLENE MONOOXYGENASE FOR THE OXIDATION OF SUBSTITUTED MONOCYCLIC AROMATIC COMPOUNDS
摘要
The invention relates to a biocatalytic process for the oxidation of substituted monocyclic aromatic compounds to the corresponding carboxylic acids and related compounds. In a preferred embodiment the invention describes a biocatalytic process to produce 4-hydroxymethylbenzoic acid and 3-hydroxymethylbenzoic acid from p-xylene and m-xylene, respectively. 4-hydroxymethylbenzoic acid has been prepared by oxidizing p-xylene with a single recombinant microorganism containing the enzyme xylene monooxygenase.
申请公布号
WO03014368(A2)
申请公布日期
2003.02.20
申请号
WO2002US27106
申请日期
2002.08.09
申请人
E.I. DU PONT DE NEMOURS AND COMPANY;BRAMUCCI, MICHAEL, G.;NAGARAJAN, VASANTHA;THOMAS, STUART, M.
发明人
BRAMUCCI, MICHAEL, G.;NAGARAJAN, VASANTHA;THOMAS, STUART, M.