MICROOROGANISMS AND CELLS FOR DIAGNOSIS AND THERAPY OF TUMORS

摘要

Described are diagnostic and pharmaceutical compositions comprising a microorganism or cell containing a DNA sequence encoding a detectable protei n or a protein capable of inducing a detectable signal, e.g. a luminescent or fluorescent protein, or a protein inducing a signal detectable by magnetic resonance imaging (MRI) or a cell receptor capable of binding a ligand and, particular embodiment, furthermore (a) DNA sequence(s) encoding (a) protein( s) suitable for tumor therapy and/or elimination of metastatic tumors, e.g. a cytotoxic or cytostatic protein.