发明名称 Sensitive, multiplexed diagnostic assays for protein analysis
摘要 Disclosed herein are methods for detecting multiple compounds in a sample, involving: (a) contacting the sample with a mixture of binding reagents, the binding reagents being nucleic acid-protein fusions, each having (i) a protein portion which is known to specifically bind to one of the compounds and (ii) a nucleic acid portion which encodes the protein portion and which includes a unique identification tag; (b) allowing the protein portions of the binding reagents and the compounds to form complexes; (c) capturing the binding reagent-compound complexes; (d) amplifying the nucleic acid portions of the complexed binding reagents; and (e) detecting the unique identification tag of each of the amplified nucleic acids, thereby detecting the corresponding compounds in the sample. Also disclosed herein are kits for carrying out such methods.
申请公布号 US2003032049(A1) 申请公布日期 2003.02.13
申请号 US20020212620 申请日期 2002.08.05
申请人 WAGNER RICHARD W. 发明人 WAGNER RICHARD W.
分类号 C12N15/10;C12Q1/68;(IPC1-7):C12Q1/68;C07K14/00 主分类号 C12N15/10
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