| 摘要 |
The invention relates to a plaster containing an active agent (1), comprising at least one cover membrane (2) and an active membrane (3) which is based on a skin-compatible matrix (4) containing a molecular sieve which is loaded with at least one active agent (Z, Z1, Z2). The molecular sieve/active agent adduct (5) releases the active agent when the active membrane comes into contact with the skin (6), in conjunction with the transpired water of the skin. The inventive plaster (1) is characterised in that the molecular sieve/active agent adduct (5) also contains water of crystallisation, to the extent that the molecular sieve is partially dehydrated compared to a sufficient basic molar quantity (m) of water of crystallisation, said molecular sieve with the reduced molar quantity (m') of water of crystallisation being loaded with the active agent (Z, Z1, Z2) so that when the active membrane (3) comes into contact with the skin (6), water is adsorbed and the active agent is desorbed, whereupon the water of crystallisation content of the molecular sieve increases. The invention also relates to various suitable embodiments of the plaster (1) containing an active agent and to an advantageous method for producing the inventive plaster (1) containing an active agent (1).
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