MOLECULAR VECTOR FOR THE GENOPHENOTYPIC CHARACTERISATION OF V3 SEQUENCES OF HIV-1 GP120 AND PROCESS FOR PREPARATION THEREOF

摘要

Recombinant vector essentially consisting of: a) a plasmid component able to carry out exactly and efficiently vector replication in bacteria and viral insert expression in eukaryotic cells; b) an HIV component characterised in that the V3 portion sequence of env gene has been deleted and substituted by Nrul enzyme restriction site. In addition the invention relates to a method for the genophenotypic evaluation of HIV genomic sequences.