摘要 |
The present invention provides a composition comprising (i) a lipid compound comprising at least one non-polar moiety and a polar moiety, wherein the non - polar moiety is of the formula X-Y-Z- wherein X is an acetylenic hydrocarbyl group containing a single C.ident.C bond, Y is O or CH2, and Z is an optiona l hydrocarbyl group, wherein the polar moiety is of the formula -[T]mPHG, wherein [T]m is an optional group selected from C(O), NH, NR1, NHC(O), C(O)N H, NR1C(O) and C(O)NR1 and CH2, where R1 is a hydrocarbyl group, wherein PHG is a polar head group, and wherein m is the number of non-polar moieties (ii) a therapeutic agent.
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