发明名称 |
PHARMACEUTICAL COMPOSITION COMPRISING LIPIDS COMPRISING A POLAR AND A NONPOLAR MOIETY |
摘要 |
The present invention provides a composition comprising (i) a lipid compound comprising at least one non-polar moiety and a polar moiety, wherein the non-polar moiety is of the formula X-Y-Z- wherein X is an acetylenic hydrocarbyl group containing a single CC bond, Y is O or CH2, and Z is an optional hydrocarbyl group, wherein the polar moiety is of the formula -[T]mPHG, wherein [T]m is an optional group selected from C(O), NH, NR1, NHC(O), C(O)NH, NR1C(O) and C(O)NR1 and CH2, where R1 is a hydrocarbyl group, wherein PHG is a polar head group, and wherein m is the number of non-polar moieties (ii) a therapeutic agent.
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申请公布号 |
WO03011252(A1) |
申请公布日期 |
2003.02.13 |
申请号 |
WO2002GB03488 |
申请日期 |
2002.07.29 |
申请人 |
MITSUBISHI CHEMICAL CORPORATION;FLETCHER, STEVEN;JORGENSEN, MICHAEL, R.;MILLER, ANDREW, DAVID |
发明人 |
FLETCHER, STEVEN;JORGENSEN, MICHAEL, R.;MILLER, ANDREW, DAVID |
分类号 |
A61K47/24;A61K9/127;A61K48/00;A61P1/00;A61P1/02;A61P1/04;A61P1/16;A61P3/00;A61P5/00;A61P7/00;A61P7/02;A61P7/04;A61P9/00;A61P9/04;A61P9/10;A61P11/02;A61P11/06;A61P13/08;A61P13/12;A61P15/00;A61P15/08;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P19/08;A61P19/10;A61P21/04;A61P25/00;A61P25/02;A61P25/06;A61P25/14;A61P25/16;A61P25/28;A61P27/02;A61P27/14;A61P27/16;A61P29/00;A61P31/00;A61P31/18;A61P35/00;A61P37/02;A61P37/04;A61P37/06;A61P37/08;A61P43/00;C07C217/06;C07F9/09;(IPC1-7):A61K9/127 |
主分类号 |
A61K47/24 |
代理机构 |
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