METHODS AND COMPOSITIONS FOR ASSESSMENT OF PULMONARY FUNCTION AND DISORDERS

摘要

The present invention is concerned with methods for the assessment of pulmonary function and/or disorders, and in particular for diagnosing predisposition to and/or severity of chronic obstructive pulmonary disease in smokers and non-smokers usins analysis of genetic polymorphisms and altered gene expression, particularly with regard to genes involved in matrix remodelling, anti-oxidant defence and the inflammatory response.