| 发明名称 |
1,3,5-TRIAZINE-2,4,6-TRIONES, PREPARATION AND USE AS GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS |
| 摘要 |
GnRH receptor antagonists of formula I are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
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| 申请公布号 |
WO03011839(A1) |
申请公布日期 |
2003.02.13 |
| 申请号 |
WO2002US24451 |
申请日期 |
2002.08.02 |
| 申请人 |
NEUROCRINE BIOSCIENCES, INC.;GUO, ZHIQIANG;WU, DONGPEI;CHEN, CHEN;TUCCI, FABIO, C.;REGAN, COLLIN |
发明人 |
GUO, ZHIQIANG;WU, DONGPEI;CHEN, CHEN;TUCCI, FABIO, C.;REGAN, COLLIN |
| 分类号 |
A61K31/53;A61P1/00;A61P3/14;A61P5/06;A61P5/24;A61P5/26;A61P5/30;A61P5/32;A61P5/34;A61P5/36;A61P9/12;A61P11/00;A61P13/08;A61P15/00;A61P15/08;A61P15/10;A61P15/18;A61P19/08;A61P25/20;A61P35/00;A61P37/02;A61P43/00;C07D251/34;C07D401/06;C07D401/12;C07D403/06;C07D403/12;C07D409/06;C07D417/04;C07D417/10;C07D417/14;(IPC1-7):C07D251/30 |
主分类号 |
A61K31/53 |
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