发明名称 |
ANTIGENS OF AND ANTIBODIES TO TRANSLOCATED MOLECULES OF MICROORGANISMS AND USES THEREOF |
摘要 |
This application describes intracellular, cytoplasmic molecules that are translocated to the surface of a microorganism and participate in binding th e microorganism to the surface of a host cell. Examples of such translocated molecules include glycerahdehyde 3-phosphate dehydrogenase, pyruvate dehydrogenase, and elongation factor-Tu. Regions oftranslocated molecules important for binding, as well as molecules which disrupt binding, are described. Antibodies directed to translocated molecules are also described.
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申请公布号 |
CA2455038(A1) |
申请公布日期 |
2003.02.13 |
申请号 |
CA20022455038 |
申请日期 |
2002.07.30 |
申请人 |
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS |
发明人 |
ALVAREZ, RENE;KANNAN, THIRUMALAI R.;BASEMAN, JOEL B. |
分类号 |
A61K38/00;A61K39/155;C07K14/47;C12N9/02;(IPC1-7):A61K39/155;A01N37/18 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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