Fluid flow cartridges, systems and methods for qualitative or quantitative analysis of a sample material are disclosed. Cartridges of the invention are constructed for fluid flow into, out of and internally throughout the cartridges. The cartridges can be used with an analytical instrument configured to interface with the instrument and present the sample or a reagent fluid at allocation and in a form appropriate for analysis of the sample by the instrument. The invention is particularly advantageous for use in analytical systems in many fields but may also be used for non-analytical purposes.
