发明名称 3-PYRIDYLETHER RERIVATIVES AND THEIR USE AS ANALGESICS
摘要 <p>A salt of general formula (I) wherein R?1, R2 and R3¿ are independently selected from the group consisting of C¿1-6? alkyl groups or any two or three of R?1, R2 and R3¿ may, together with the nitrogen to which they are attached, form a heterocyclic ring. R4 is a selected from the group of moieties which are effective to alter the solubility of the compound in physiological fluids and pharmaceutical carries, n is an integer of 0 to 5, A is selected from hydrogen or may, with the carbon to which it is attached and with any one of R?1, R2 and R3¿ and the nitrogen to which they are attached, form a heterocyclic ring X is a negatively charged counterion and p is the number of negative charges thereon, the number of molecules of the positively charged tertiary amino ion being equal to the integer p in any given salt. Preferably the salt is of formula (II) below.</p>
申请公布号 WO2003011828(A2) 申请公布日期 2003.02.13
申请号 US2002023686 申请日期 2002.07.25
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