Pharmaceutical composition containing caspase-8 and /or caspase-9 useful for overcoming glucocorticoid- and cancer therapy-induced apoptosis of tumours

摘要

Described are pharmaceutical compositions containing a caspase-8 and/or caspase-9 protein and/or (a) DNA sequence(s) encoding a caspase-8 and/or caspase-9 protein and a suitable pharmaceutical carrier. Said compositions are useful for restoring apoptosis sensitivity of glucorticoid-induced resistance of carcinoma cells towards cytotoxic therapy.