发明名称 |
Process for the preparation of 2,5-bis-(2,2,2-trifluoroethoxy)-n-(2-piperidyl-methyl)-benzamide (flecanide) |
摘要 |
<p>Process for the synthesis of FLECAINIDE comprising the reaction between 2,5-dihydroxybenzoic acid with trifluoroethanol perfluorobutanesulphonate to give the intermediate trifluoroethanol 2,5-bis-trifluoroethoxybenzoate, the reaction of said intermediate with 2-aminomethylpiperidine to give FLECAINIDE.</p> |
申请公布号 |
EP1283201(A1) |
申请公布日期 |
2003.02.12 |
申请号 |
EP20020017837 |
申请日期 |
2002.08.08 |
申请人 |
A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.P.A. |
发明人 |
VIGANO', ENRICO;PIZZATTI, ENRICA;MOLTENI, RENATO;LANFRANCONI, SIMONA |
分类号 |
C07D211/26;(IPC1-7):C07D211/26 |
主分类号 |
C07D211/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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