| 摘要 |
<p>The present invention provides a solid preparation comprising a crystal of [3 [(2R) [[(2R) (3 chlorophenyl) 2 hydroxyethyl]amino]propyl]mi nus;1H indol 7 yloxy]acetic acid (Compound A), especially a crystal of Compound A having a particle size of not larger than 100 mgr;m at the cumulative weight distribution value of 50 %, and not larger than 200 mgr;m at the cumulative weight distribution value of 95 %, preferably a solid preparation having the excellent stability and the content uniformity of Compound A, which is prepared by preparing granules of the crystal of Compound A with fillers, disintegrants and binders, and then followed by mixing said granules with external excipients.</p> |
