QUICK-DISINTEGRATING TABLET IN THE BUCCAL CAVITY AND MANUFACTURING METHOD THEREOF

摘要

Tablets quickly disintegrating in the oral cavity which contain a drug, a diluent and a saccharide having a melting point lower than the melting point s of the drug and the diluent, wherein the low-melting saccharide is uniformly dispersed in the tablets and crosslinkage of the low-melting saccharide, whi ch has been once molten and solidified, is formed among particles of the drug and/or the diluent. Compared with the conventional tablets quickly disintegrating in the oral cavity, the above tablets have an enhanced tablet strength and an improved abrasion resistance without prolonging the disintegration time in the oral cavity.