发明名称 |
HUMANIZED IMMUNOGLOBULIN REACTIVE WITH B7 MOLECULES AND METHODS OF TREATMENT THEREWITH |
摘要 |
The invention relates to humanized anti-B7-2 and anti-B7-1 antibodies, wherein each comprise a variable region of non-human origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies. |
申请公布号 |
PL350909(A1) |
申请公布日期 |
2003.02.10 |
申请号 |
PL20000350909 |
申请日期 |
2000.02.09 |
申请人 |
GENETICS INSTITUTE,INC. |
发明人 |
CO MAN SUNG;VASQUEZ MAXIMILIANO;CARRENO BEATRIZ;CELNIKER ABBIE CHERYL;COLLINS MARY;GOLDMAN SAMUEL;GRAY GARY S.;KNIGHT ANDREA;O'HARA DENISE;RUP BONITA;VELDMAN GEERTRUIDA M. |
分类号 |
G01N33/53;A61K31/436;A61K31/519;A61K31/573;A61K35/14;A61K35/28;A61K38/00;A61K39/00;A61K39/395;A61K45/00;A61P1/04;A61P1/18;A61P3/00;A61P3/10;A61P7/00;A61P7/06;A61P11/06;A61P17/00;A61P19/02;A61P25/00;A61P29/00;A61P31/00;A61P35/00;A61P35/02;A61P37/00;A61P37/02;A61P37/06;C07K16/00;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;G01N33/533;G01N33/534;G01N33/535;(IPC1-7):C07K16/28;C12N15/13;C12N15/62 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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