SELF-AMPLIFYING PHARMACOLOGICALLY CONTROLLABLE EXPRESSIVE SYSTEMS

摘要

FIELD: medicine. SUBSTANCE: system is nucleic acid structure showing self- amplifying expressive properties. It has at least one first structural gene encoding active substance, at least one second structural gene encoding transcription factor protein and at least one activating sequence composed of at least one sequence binding the transcription factor protein and at least one promotion sequence. Each activating sequence stimulates structural gene expression and transcription factor protein expression. EFFECT: enhanced effectiveness in producing medicaments on the basis of the nucleic acid structure. 34 cl, 16 dwg, 1 tbl