发明名称 To detect a complex or hybrid between two molecules, on a biochip surface, a chemical/biological agent is used which generates a fluorescent signal to be converted into a chemical signal and an electrical signal
摘要 Detecting a complex or hybrid formed by at least two molecules, on a solid carrier surface of a biochip, where one molecule is attached to the surface as a search molecule and the other is in a sample solution as the target molecule, is new. Detecting a complex or hybrid formed by at least two molecules, on a solid carrier surface (3) of a biochip, where one molecule is attached to the surface as a search molecule (8) and the other is in a sample solution as the target molecule (9). A chemical or biological agent (10) is used, specifically linked to the developed complex or hybrid. The complex/hybrid is excited, so that the agent emits a fluorescent signal (11). The luminescence is detected and converted into a chemical signal (15) at the biochip level, to be registered (6) as an electrical signal (12) for analysis. The chemical signal is generated by a metal precipitation, preferably of silver halide.
申请公布号 FR2828284(A1) 申请公布日期 2003.02.07
申请号 FR20010010302 申请日期 2001.08.01
申请人 BIO MERIEUX 发明人 GARNIER FRANCIS;MANDRAND BERNARD
分类号 B01L3/00;C12Q1/68;C40B70/00;G01N21/64;G01N21/78;G01N33/53;G01N33/543;G01N35/00;G01N37/00;(IPC1-7):G01N33/543 主分类号 B01L3/00
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