A dibromomethyl moiety is converted to a sulfonylmethyl moiety by treatment with a sulfinic acid salt. For example, (methyl-sulfonyl)methyl bromo-quinoline is prepared by the treatment of dibromomethyl bromo-quinoline with a sulfinic acid salt.
申请公布号
WO03010137(A1)
申请公布日期
2003.02.06
申请号
WO2002US23308
申请日期
2002.07.19
申请人
MERCK & CO., INC.;XU, FENG;SAVARY, KIMBERLY, A.;WILLIAMS, JOHN, M.