NOVEL TARGETED DELIVERY SYSTEM FOR BIOACTIVE AGENTS

摘要

Novel targeted delivery systems for bioactive agents. In preferred form, the delivery systems comprise, in combination with an effective amount of a bioactive agent, a targeted matrix comprising a polymer and a targeting ligand. Preferably, the targeting ligand is covalently associated with the polymer and the bioactive agent is associated non-covalently with the polyme r. Also in preferred embodiments, the bioactive agent is substantially homogeneously dispersed throughout the matrix. The compositions are particularly suitable as delivery vehicles with bioactive agents that have limited water solubility .