发明名称 |
Emulsion vehicle for poorly soluble drugs |
摘要 |
An emulsion of alpha-tocopherol, stabilized by biocompatible surfactants, as a vehicle or carrier for therapeutic drugs, which is substantially ethanol free and which can be administered to animals or humans various routes is disclosed. Also included in the emulsion is PEGylated vitamin E. PEGylated alpha-tocopherol includes polyethylene glycol subunits attached by a succinic acid diester at the ring hydroxyl of vitamin E and serves as a primary surfactant, stabilizer and a secondary solvent in emulsions of alpha-tocopherol.
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申请公布号 |
US2003027858(A1) |
申请公布日期 |
2003.02.06 |
申请号 |
US20020151064 |
申请日期 |
2002.05.17 |
申请人 |
SONUS PHARMACEUTICALS, INC. |
发明人 |
LAMBERT KAREL J.;CONSTANTINIDES PANAYIOTIS P.;QUAY STEVEN C. |
分类号 |
A61K9/107;A61K9/48;A61K31/337;A61K47/22;A61K47/30;(IPC1-7):A61K31/355 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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