发明名称 |
SUBSTITUTED 1, 3, 5-TRIAZINES AND PYRIMIDINES AS ABCA-1 ELEVATING COMPOUNDS AGAINST CORONARY ARTERY DISEASE OR ATHEROSCLEROSIS |
摘要 |
The present invention provides compounds that elevate cellular expression of the ABCA-1 gene, promoting cholesterol efflux from cells and increasing HDL levels in the plasma of a mammal, in particular humans. The compounds are useful for treating coronary artery disease. |
申请公布号 |
WO0246172(A3) |
申请公布日期 |
2003.02.06 |
申请号 |
WO2001US46387 |
申请日期 |
2001.12.03 |
申请人 |
CV THERAPEUTICS, INC. |
发明人 |
CAMPBELL, MICHAEL;ZABLOCKI, JEFF, A.;IBRAHIM, PRABHA, N. |
分类号 |
A61K45/00;A61K31/085;A61K31/136;A61K31/16;A61K31/165;A61K31/167;A61K31/17;A61K31/18;A61K31/357;A61K31/435;A61K31/47;A61K31/472;A61K31/495;A61K31/505;A61K31/506;A61K31/53;A61K45/06;A61P3/06;A61P9/00;A61P9/10;A61P43/00;C07C237/04;C07C237/06;C07C237/22;C07C237/40;C07C275/26;C07C311/20;C07C323/36;C07C323/40;C07C323/60;C07C327/42;C07C327/44;C07C327/48;C07C335/16;C07D215/38;C07D217/24;C07D239/48;C07D251/16;C07D251/22;C07D251/52;C07D319/08;C07D319/18;C07D401/12;C07D405/12;C07D409/12;C07D409/14;C07D413/12;C07D413/14 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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