发明名称 SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR
摘要 Selected substituted piperazine compounds are effective for prophylaxis and treatment of diseases, such as obesity and the like. The invention encompass es novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatme nt of diseases and other maladies or conditions involving activation of the melanocortin receptor. The subject invention also relates to processes For making such compounds as well as to intermediates useful in such processes.< /SDOAB>
申请公布号 CA2454903(A1) 申请公布日期 2003.02.06
申请号 CA20022454903 申请日期 2002.07.25
申请人 AMGEN INC. 发明人 HAN, NIANHE;XU, SHIMIN;FOTSCH, CHRISTOPHER H.;BO, YUNXIN;ARASASINGHAM, PREMILLA;LIU, QINGYIAN;CHEN, NING;NORMAN, MARK H.;KELLY, MICHAEL G.;TAMAYO, NURIA;STEC, MARKIAN;SMITH, DUNCAN M.;GOLDBERG, MARTIN H.;XI, NING;HSIEH, FENG-YIN
分类号 C07D295/18;A61K31/495;A61K31/496;A61K31/5377;A61K38/00;A61P3/04;A61P3/10;A61P43/00;C07D205/04;C07D207/08;C07D207/09;C07D209/14;C07D209/18;C07D209/42;C07D211/26;C07D211/60;C07D211/62;C07D213/38;C07D213/81;C07D213/82;C07D215/48;C07D217/06;C07D217/14;C07D217/26;C07D233/54;C07D233/64;C07D295/185;C07D317/60;C07D317/68;C07D319/16;C07D319/18;C07D401/12;C07D403/12;C07D409/12;C07D413/12;C07D417/12;C07D451/02;C07D487/08;C07K5/06;C07K5/078;(IPC1-7):C07D403/12;C07K5/062;C07K5/065;C07D401/14;A61K31/55;A61K31/551 主分类号 C07D295/18
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