发明名称 |
Process for the preparation of the sodium salt of 6[D-(-)alpha-4-(ethyl-2,3-dioxo-1-piperazinocarbonyl-amino)phenylacetamido]penicillanic acid |
摘要 |
<p>The present invention refers to the preparation process of the sodium salt of 6ÄD-(-) alpha -4-(ethyl-2,3-dioxo-1-piperazinocarbonylamino) phenylacetamidoÜpenicillanic acid, comprising the reaction of the acid with a reagent selected from the group consisting of sodium hydroxide, sodium carboxylates and sodium alcoholates, followed by a separation step of the so obtained sodium salt by precipitation.</p> |
申请公布号 |
EP1281713(A1) |
申请公布日期 |
2003.02.05 |
申请号 |
EP20020017375 |
申请日期 |
2002.08.02 |
申请人 |
ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.P.A. |
发明人 |
BRANDT, ALBERTO;CECCHETELLI, LOREDANA;CORSI, GIORDANO BRUNO;SIMEONI, ANTONIO |
分类号 |
C07D499/00;C07D499/14;C07D499/16;C07D499/68;C07D499/76;(IPC1-7):C07D499/16 |
主分类号 |
C07D499/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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