发明名称 Fused cycloheptane and fused azacycloheptane compounds and their methods of use
摘要 The invention comprises novel compounds that are effective in the prophylaxis and treatment of diseases, such as integrin receptors mediated diseases, in particular, diseases or conditions mediated by integrin receptors, such as alphavbeta3, alphavbeta5, alphavbeta6 and the like. The invention encompasses novel compounds, pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of such diseases and disorders. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
申请公布号 US6514964(B1) 申请公布日期 2003.02.04
申请号 US20000671025 申请日期 2000.09.26
申请人 AMGEN INC. 发明人 CHEN ZHIDONG;DOMINGUEZ CELIA;GRENZER-LABER ELLEN;HAN NIANHE;LIU LONGBING;MORENO OFIR A.;RUTLEDGE MELVIN C.;TASKER ANDREW S.
分类号 A61K31/55;A61P7/00;A61P9/00;A61P9/10;A61P17/02;A61P19/08;A61P27/02;A61P29/00;A61P31/12;A61P35/00;A61P35/04;A61P43/00;C07D213/74;C07D223/16;C07D401/12;C07D401/14;C07D403/06;C07D403/12;C07D405/06;C07D405/14;C07D417/12;C07D471/04;C07D471/14;C07D487/04;C07D519/00;(IPC1-7):C07D223/16 主分类号 A61K31/55
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