发明名称 |
Hedgehog interacting proteins and uses related thereto |
摘要 |
The present invention concerns the discovery of a new family of hedgehog binding proteins, refered to herein as "hedgehog interacting proteins" or "HIPs", which are demonstrated to bind to hedgehog polypeptides with high affinity. As described herein, the vertebrate HIP proteins exhibit spatially and temporally restricted expression domains indicative of important roles in hedgehog-mediated induction.
|
申请公布号 |
US6514724(B1) |
申请公布日期 |
2003.02.04 |
申请号 |
US19970933711 |
申请日期 |
1997.09.19 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
MCMAHON ANDREW P.;CHUANG PAO-TIEN |
分类号 |
G01N33/50;A61K38/00;A61K48/00;A61P43/00;C07K14/46;C07K14/705;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/02;C12N15/09;C12N15/12;C12P21/02;C12Q1/68;G01N33/15;G06F13/42;(IPC1-7):C12P21/06 |
主分类号 |
G01N33/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|