FRACTIONATING APPARATUS HAVING COLONIES OF PILLARS ARRANGED IN MIGRATION PASSAGE AT INTERVAL AND PROCESS FOR FABRICATING PILLARS

摘要

A fractionating apparatus is used for fractionating sample into microstru c- tures different in size, and includes a fractionating unit formed with a fra c- tionating passage; the fractionating passage is defined in a groove formed i n a substrate of the fractionating unit, and pillar patches (121) are formed in the groove at intervals wider than the gap among the pillar patches (121); while the sample is migrated through the fractionating passage, small-sized DNA molecules (S) are trapped in the pillar patches (121), and large-sized DNA molecules (L) are smoothly migrated through the wide intervals; this results in that the large-sized DNA molecules (L) reaches the end of the fractionati ng passage faster than the small-sized DNA molecules without clogging.