Lipid-containing compositions and uses thereof

摘要

A lipid-containing liquid composition comprising a membrane-forming polar lipid dispersed in an aqueous medium together with a synthetic amphipathic polymer that interacts with the polar lipid to produce a polymer/lipid complex. The polymer interacts with and solubilizes the polar lipid in the aqueous medium at a pH that is below a critical lipid-solubilizing value and at a temperature above a predetermined phase transition temperature dependant upon the polar lipid. The composition is pH variable, such that the pH can be raised from below the critical lipid-solubilizing value to above the critical lipid-solubilizing value by addition of alkaline reagent.