| 发明名称 |
HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR |
| 摘要 |
Compounds of formula wherein X, Y and Z are independently selected from the group consisting of N, O, S, C and CO wherein at least one X, Y and Z is heteroatom; Ar1 and Ar2 are independently selected from the group consisting of a heterocyclic or fused heterocyclic moiety and an aromatic moiety; acts as antagonist at metabotropic glutamate receptor, and are useful for treating neurological diseases and disorders. 30 claims
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| 申请公布号 |
BG106493(A) |
申请公布日期 |
2003.01.31 |
| 申请号 |
BG20020106493D |
申请日期 |
2002.03.07 |
| 申请人 |
NPS PHARMACEUTICALS INC. |
发明人 |
VAN WAGENEN, BRADFORD C.;STORMANN, THOMAS M.;MOE, SCOTT T.;SHEEHAN, SUSAN M.;MCLEOD, DONALD A.;SMITH, DARYL L.;ISAAC, METHVIN B.;SLASSI, ABDELMALIK |
| 分类号 |
A61K;A61K31/4245;A61K31/4439;A61K31/4709;A61K31/4725;A61K31/497;A61P;A61P9/10;A61P25/00;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/28;A61P29/00;C07D;C07D401/04;C07D403/04;C07D413/04;(IPC1-7):C07D413/04;A61K31/443;A61K31/472 |
主分类号 |
A61K |
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