| 摘要 |
The invention provides a method for the probabilistic scoring of SNPs for prioritization of target genes and proteins. The invention includes a method for identifying and evaluating a polynucleotide sequence encoding a polypeptide or a non-coding sequence to predict a correlation with a pathological state. A probabilistic scoring mechanism is used for the evaluation of the biological significance of SNPs and the use of this score for the prioritization of target genes and proteins.
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