| 摘要 |
<p>Compounds represented by the general formula (I) or salts thereof: (I) [wherein R1 is hydrogen, optionally substituted C1-C10 alkyl, or an N-protecting group; R2 is optionally substituted C1-C10 alkyl or optionally substituted C2-C10 alkenyl; R3 and R4 are each independently hydrogen or a hydroxyl-protecting group; X is -N(R5)R6 or a residue derived from the amino group of an amino acid or a peptide (wherein R5 and R6 are each independently hydrogen, optionally substituted C1-C10 alkyl, or optionally substituted C3-C12 cycloalkyl); and Y is hydrogen, -CH2NH2, -CONH2, or -COOH]. The compounds are useful as specific inhibitors against sugar chain related enzymes including glycosyltransferase and glycosidase, and effective in treatment or prevention of diseases in which sugar chain related enzymes participate.</p> |
