NOVEL TRANSFORMED CELLS,METHOD OF SCREENING ANTIAGING AGENT AND ANTIAGING AGENTS

摘要

Novel transformed cells which are useful in constructing a system of screening an antiaging agent; a screening method using the same; and antiaging agents. Namely, transformed cells constructed by transferring into normal cells a gene encoding (a) a protein capable of phosphorylating p38 protein, or (b) the p38 protein, a variant of the p38 protein, the kinase domain of the p38 protein, the kinase domain of a p38 protein variant or a fused protein containing the same; a screening method using these transformed cells; and antiagaing agents containing as the active ingredient compounds obtained by the screening method.